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PD-M6

CAT: 0013-GTR19257786-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257786-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PD-M6 is an mTOR PROTAC degrader with a DC50 of 4.8 μM, which facilitates the ubiquitination and degradation of mTOR. It inhibits the proliferation of cancer cell lines HeLa, MCF-7, and HepG2 with IC50 values of 11.3, 2.58, and 3.23 μM, respectively, and induces autophagy. Additionally, PD-M6 specifically targets the degradation of the key protein LAMTOR1 in the mTOR signaling pathway.
CAS Number
3058330-82-5
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) C (N2C (=O) C=3C=CC=C (NCCCCCCNC=4N=C (N=C (N4) N5CCOCC5) N6CCOCC6) C3C2=O) CC1
Molecular Formula
C30H39N9O6
Molecular Weight
621.69
Storage Conditions
-20°C
Notes
For research use only.

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