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SARS-CoV-2 Mpro-IN-41

CAT: 0013-GTR19257672-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257672-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM) . This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.
Field of Research
Immunology & Inflammation, Infectious Disease & Virology, Neuroscience
Molecular Formula
C27H23ClN4O3S
Storage Conditions
-20°C
Notes
For research use only.

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