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TBK1-IN-2

CAT: 0013-GTR19257626-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257626-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TBK1-IN-2 (Compound A1) is a potent inhibitor of TBK1 with an IC50 of 775 pM. It binds to TBK1 through stable hydrogen bonding and π-π stacking interactions, thereby inhibiting the phosphorylation of IRF3. TBK1-IN-2 works in synergy with TNF/IFNγ to enhance immune-mediated tumor cell death and is applicable in cancer immunotherapy research.
CAS Number
3075572-35-6
Field of Research
Signal Transduction
Smiles
O=C (OCC=1C=CC=CC1) NC2CCN (C (=O) NC3=CNN=C3C4=NC=5C=C (OC) C (OC) =CC5N4) CC2
Molecular Formula
C26H29N7O5
Molecular Weight
519.55
Storage Conditions
-20°C
Notes
For research use only.

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