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CYP2E1-IN-1

CAT: 0013-GTR19257587-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257587-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CYP2E1-IN-1 (Compound 10) is an orally active inhibitor of cytochrome P450 2E1 (CYP2E1) with a dissociation constant (Kd) of 7.02 μM, an IC50 of 1.64 μM, and a Ki of 0.897 μM. It alleviates pancreatic damage by activating the Nrf2/HO-1 signaling pathway and inhibiting ROS production. CYP2E1-IN-1 demonstrates significant anti-inflammatory and antioxidant properties, effectively reducing inflammation and oxidative stress in severe acute pancreatitis (SAP) . It is suitable for the study of SAP and other inflammation-related conditions.
CAS Number
38205-55-9
Field of Research
Immunology & Inflammation, Metabolism Research, Signal Transduction
Smiles
O=C (C=1SC=NC1C) C
Molecular Formula
C6H7NOS
Molecular Weight
141.19
Storage Conditions
-20°C
Notes
For research use only.

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