Products for Research Use Only
RegisterLogin

HQY1428

CAT: 0013-GTR19257582-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19257582-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
HQY1428 is an orally active CDK12 inhibitor. It impedes DNA replication, causing cell cycle arrest at the G2/M phase in SKOV3 cells, and induces DNA double-strand breaks as well as apoptosis. In the SKOV3 xenograft mouse model, HQY1428 demonstrates antitumor activity. Additionally, when combined with the HER2 inhibitor Lapatinib in the NCI-N87 xenograft mouse model, HQY1428 produces a synergistic therapeutic effect.
Field of Research
Cell Biology, Molecular Biology
Molecular Formula
C25H28ClFN6O3S
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T207664-01HQY1428

Popular Products