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PARP14 inhibitor 2

CAT: 0013-GTR19258423-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258423-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP14 inhibitor2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of less than 30 nM. It effectively inhibits the mono ADP-ribosyltransferase activity of PARP14 and modulates IFN-γ and IL-4 signaling, thereby reversing pro-tumor macrophage polarization and suppressing anti-tumor inflammatory responses. PARP14 inhibitor2 holds potential for research in PARP14-related conditions such as tumors, atopic dermatitis, and autoimmune diseases.
CAS Number
3064731-00-3
Field of Research
Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery
Smiles
O=C1N=C (NC2=CC (OCC34CCC (NC (=O) C) (CC3) CC4) =CC (F) =C12) CSC5CCOCC5
Molecular Formula
C25H32FN3O4S
Molecular Weight
489.60
Storage Conditions
-20°C
Notes
For research use only.

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