Puma BH3 Domain Peptide

• Description:

  Puma BH3 Domain Peptide_x000D_ Catalog number: B2012684_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 500 ug_x000D_ Molecular Weight or Concentration: N/A_x000D_ Supplied as: Lyophilized Powder_x000D_ Applications: molecular tool for various biochemical applications_x000D_ Storage: 2-8°C_x000D_ Keywords: Bcl-2-binding component 3, p53 up-regulated modulator of apoptosis, Bbc3, Puma_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M. Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome Prog Neurobiol. 2013 Jul-Aug;106-107:33-54._x000D_ 2: Han CW, Lee HN, Jeong MS, Park SY, Jang SB. Structural basis of the p53 DNA binding domain and PUMA complex Biochem Biophys Res Commun. 2021 Apr 9;548:39-46._x000D_ 3: Wu X, Deng Y. Bax and BH3-domain-only proteins in p53-mediated apoptosis Front Biosci. 2002 Jan 1;7:d151-6._x000D_ 4: Delgado-Soler L, Pinto M, Tanaka-Gil K, Rubio-Martinez J. Molecular determinants of Bim(BH3) peptide binding to pro-survival proteins J Chem Inf Model. 2012 Aug 27;52(8):2107-18._x000D_ 5: Day CL, Smits C, Fan FC, Lee EF, Fairlie WD, Hinds MG. Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1 J Mol Biol. 2008 Jul 25;380(5):958-71._x000D_ 6: Lee EF, Smith BJ, Horne WS, Mayer KN, Evangelista M, Colman PM, Gellman SH, Fairlie WD. Structural basis of Bcl-xL recognition by a BH3-mimetic α/β-peptide generated by sequence-based design Chembiochem. 2011 Sep 5;12(13):2025-32._x000D_ 7: Holzerland J, Fénéant L, Banadyga L, Hölper JE, Knittler MR, Groseth A. BH3-only sensors Bad, Noxa and Puma are Key Regulators of Tacaribe virus-induced Apoptosis PLoS Pathog. 2020 Oct 12;16(10):e1008948._x000D_ 8: Stadler LK, Tomlinson DC, Lee T, Knowles MA, Ko Ferrigno P. The use of a neutral peptide aptamer scaffold to anchor BH3 peptides constitutes a viable approach to studying their function Cell Death Dis. 2014 Jan 30;5(1):e1037._x000D_ 9: Liu Y, Li Y, Wang H, Yu J, Lin H, Xu D, Wang Y, Liang A, Liang X, Zhang X, Fu M, Qian H, Lin C. BH3-based fusion artificial peptide induces apoptosis and targets human colon cancer Mol Ther. 2009 Sep;17(9):1509-16._x000D_ 10: Plötz M, Hossini AM, Gillissen B, Daniel PT, Stockfleth E, Eberle J. Mutual regulation of Bcl-2 proteins independent of the BH3 domain as shown by the BH3-lacking protein Bcl-x(AK) PLoS One. 2012;7(4):e34549. _x000D_ _x000D_ Products Related to Puma BH3 Domain Peptide can be found at Peptides

• Short Description:

  Catalog Number: B2012684 (500 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5