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NPS-2143 (SB 262470A)

CAT: 0013-GTR19259644-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19259644-01Size:100 mg
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Description
NPS-2143 (SB 262470A) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.
CAS Number
284035-33-2
Field of Research
Neuroscience
Purity
>98%
Smiles
N#CC1=C (OC[C@@H] (CNC (C) (CC2=CC=C3C=CC=CC3=C2) C) O) C=CC=C1Cl
Molecular Formula
C24H25N2O2CL
Molecular Weight
408.9205
Notes
For research use only.

Chemical Information

Nps-2143
CAS Number284035-33-2
PubChem CID6918446
IUPAC Name2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]benzonitrile
Molecular FormulaC24H25ClN2O2
Molecular Weight408.9
XLogP5
Topological Polar Surface Area65.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Heavy Atom Count29
Formal Charge0
Complexity560
SMILES
CC(C)(CC1=CC2=CC=CC=C2C=C1)NC[C@H](COC3=C(C(=CC=C3)Cl)C#N)O
InChI
InChI=1S/C24H25ClN2O2/c1-24(2,13-17-10-11-18-6-3-4-7-19(18)12-17)27-15-20(28)16-29-23-9-5-8-22(25)21(23)14-26/h3-12,20,27-28H,13,15-16H2,1-2H3/t20-/m1/s1
InChIKey
PZUJQWHTIRWCID-HXUWFJFHSA-N
Chemical Structure
2D Structure
2D structure of Nps-2143
CAS: 284035-33-2
CID: 6918446
Formula: C24H25ClN2O2
MW: 408.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight408.9
XLogP35
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Exact Mass408.1604557
Monoisotopic Mass408.1604557
Topological Polar Surface Area65.3 Ų
Heavy Atom Count29
Formal Charge0
Complexity560
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

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MBS130674-01NPS-2143(SB 262470A )
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HY-10007RNPS-2143 (Standard)

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