Products for Research Use Only

PSSI-51

CAT: 0013-GTR19258027-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258027-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PSSI-51 is an orally active inhibitor of succinyl-CoA:3-ketoacid CoA transferase (SCOT) with selectivity for peripheral tissues. It effectively inhibits SCOT activity in peripheral tissues such as muscle and kidney, without affecting SCOT activity in brain tissue. By inhibiting SCOT, PSSI-51 reduces ketone body oxidation, thereby improving obesity-related hyperglycemia. It shows potential for research in type 2 diabetes (T2D) and in addressing obesity-related metabolic disorders.
Smiles
FC1=CC=C (C (C2=CC=C (F) C=C2) N3CCN (CCCN4C (C (C=CC=C5) =C5C4=O) =O) CC3) C=C1.Cl.Cl
Molecular Formula
C28H29Cl2F2N3O2
Molecular Weight
548.45
Storage Conditions
-20°C
Notes
For research use only.