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RMC5127

CAT: 0013-GTR19250746-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250746-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RMC5127 is a brain-penetrant, oral inhibitor selectively targeting the KRAS G12V mutation. It blocks oncogenic RAS signaling, triggering apoptosis in mutant cells, and demonstrates antitumor efficacy in both cellular and animal models of KRAS G12V-driven cancers.
CAS Number
3056146-38-1
Product Name Alternative
RMC-5127, RMC 5127
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
97.54% (May vary between batches)
Solubility
DMSO:100 mg/mL (94.13 mM)
Smiles
C[C@H] (OC) C (N=C1) =[C@@] ([C@@]2=C (CC (C) (C) COC ([C@H]3NN (C ([C@@H] (NC ([C@H]4OC[C@@H]4C) =O) [C@H]5N6CC7 (COC7) C6) =O) C8CC3C8) =O) C9=C (C=CC (C%10=CSC5=N%10) =C9) N2CCOC%11CCOCC%11) C=C1N%12CCN (C%13CC%13) CC%12
Molecular Formula
C57H75N9O9S
Molecular Weight
1062.32
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
T204085-01RMC5127

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