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YB-3–17

CAT: 0013-GTR19250547-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250547-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
YB-3-17 is a potent bifunctional molecule acting as an mTOR inhibitor (IC50=0.22 nM) and a GSPT1 degrader (DC50=5 nM) . It demonstrates nanomolar antiproliferative activity in glioblastoma cell lines and has shown antitumor efficacy in mouse models, supporting its use in oncology and targeted protein degradation research.
CAS Number
2940242-88-4
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2=O) NCC4CCC (C (=O) N5CCC (N6N=C (C=7C=CC=8OC (=NC8C7) N) C=9C (=NC=NC96) N) CC5) CC4) CC1
Molecular Formula
C38H39N11O6
Molecular Weight
745.786
Storage Conditions
-20°C
Notes
For research use only.

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