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Polθ-IN-7

CAT: 0013-GTR19250533-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250533-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Polθ-IN-7 (example 12) is a potent and selective small-molecule inhibitor of DNA polymerase theta (Polθ), exhibiting a Ki value of 1.27 nM. This inhibitor is a valuable research tool for studying DNA repair mechanisms, particularly in the context of targeting homologous recombination-deficient cancers in both cellular and biochemical assays.
CAS Number
2923356-52-7
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology
Smiles
O=C1[C@]2 (N (C (=O) C[C@@]2 (CN (CCN3CCN (C) CC3) C=4C (N1C) =CC=CC4C) [H]) C5=CC (C (F) (F) F) =CC (C) =N5) [H]
Molecular Formula
C28H35F3N6O2
Molecular Weight
544.612
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
HY-153755Polθ-IN-7
sc-17770POL H (B-7)
sc-137021DNA pol α (D-7)
sc-17770 FITCPOL H (B-7) FITC
sc-17770 ACPOL H (B-7) AC
sc-390583DNA pol δ 2 (D-7)
sc-390804DNA pol δ 2 (E-7)
sc-137021 PEDNA pol α (D-7) PE
sc-137021 HRPDNA pol α (D-7) HRP
sc-137021 FITCDNA pol α (D-7) FITC

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