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HL001

CAT: 0013-GTR19250509-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250509-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HL001 is a dual cyclophilin A inhibitor and LPA1 receptor antagonist that stabilizes p53 via G3BP1 downregulation and MDM2-p53 disruption, inducing tumor cell apoptosis. It demonstrates antitumor activity in research models and is also applied in studies of pulmonary fibrosis.
CAS Number
1186371-31-2
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Smiles
O=C (NC (=O) C=1C (O) =CC=CC1O) NC2C=3C=CC=CC3C=4C=CC=CC42
Molecular Formula
C21H16N2O4
Molecular Weight
360.363
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-((9H-Fluoren-9-yl)carbamoyl)-2,6-dihydroxybenzamide
CAS Number1186371-31-2
PubChem CID44249305
IUPAC NameN-(9H-fluoren-9-ylcarbamoyl)-2,6-dihydroxybenzamide
Molecular FormulaC21H16N2O4
Molecular Weight360.4
XLogP4.1
Topological Polar Surface Area98.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count27
Formal Charge0
Complexity536
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)NC(=O)NC(=O)C4=C(C=CC=C4O)O
InChI
InChI=1S/C21H16N2O4/c24-16-10-5-11-17(25)18(16)20(26)23-21(27)22-19-14-8-3-1-6-12(14)13-7-2-4-9-15(13)19/h1-11,19,24-25H,(H2,22,23,26,27)
InChIKey
ZYTNFBHCEBPFQV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-((9H-Fluoren-9-yl)carbamoyl)-2,6-dihydroxybenzamide
CAS: 1186371-31-2
CID: 44249305
Formula: C21H16N2O4
MW: 360.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight360.4
XLogP34.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass360.11100700
Monoisotopic Mass360.11100700
Topological Polar Surface Area98.7 Ų
Heavy Atom Count27
Formal Charge0
Complexity536
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
M10634HL001

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