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(rac) -Talazoparib

CAT: 0013-GTR19250428-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250428-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(rac) -Talazoparib is a potent, orally bioavailable PARP1/2 inhibitor with low nanomolar Ki values. It effectively blocks cellular PARylation, induces DNA damage accumulation, and inhibits proliferation in BRCA-deficient cell lines. This compound has also demonstrated in vivo antitumor efficacy in mouse xenograft models.
CAS Number
1207454-56-5
Field of Research
Epigenetics & Chromatin, Molecular Biology, Signal Transduction
Smiles
O=C1NN=C2C=3C (=CC (F) =CC13) NC (C4=CC=C (F) C=C4) C2C5=NC=NN5C
Molecular Formula
C19H14F2N6O
Molecular Weight
380.351
Storage Conditions
-20°C
Notes
For research use only.

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