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XYD049

CAT: 0013-GTR19249637-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249637-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
XYD049 (compound 7d) is a CRBN-based molecular glue degrader of GSPT1 with potent activity against MYC-driven castration-resistant prostate cancer (CRPC) . It demonstrates strong in vitro growth inhibition of 22Rv1 cells and in vivo antitumor efficacy by downregulating key oncoproteins like AR-v7 and c-Myc.
CAS Number
3006788-11-7
Field of Research
Pharmacology & Drug Discovery
Smiles
O=C (NCCCCCNC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3) COC4=CC=5ON=C (C5C=C4NS (=O) (=O) C6=CC (Br) =CC=C6OC) C
Molecular Formula
C35H35BrN6O10S
Molecular Weight
811.656
Storage Conditions
-20°C
Notes
For research use only.

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