YW-N-7 TFA

CAT: 0013-GTR19250446-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19250446-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

YW-N-7 (TFA) is a potent RET-targeting PROTAC degrader with a DC50 of 88 nM. It effectively inhibits RET kinase activity and demonstrates robust antitumor efficacy in KIF5B-RET xenograft models, supporting its use in oncology research for studying RET-driven cancers both in vitro and in vivo.

Field of Research

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C58H63F3N12O9

Molecular Weight

1129.19

Storage Conditions

-20°C

Notes

For research use only.

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