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CQ1373

CAT: 0013-GTR19249528-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249528-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CQ1373 is a potent and selective RET inhibitor effective against wild-type and solvent front mutants (G810C/R), with cellular IC50 values in the low nM range. It inhibits RET phosphorylation and downstream signaling, inducing apoptosis and cell cycle arrest in vitro, supporting its investigation in RET-driven cancer research.
Field of Research
Cell Biology, Signal Transduction
Smiles
COC1=CC (C2=C (/C=C/C3=CC (Cl) =C (NC (NC4=NOC (C (C) (C (F) (F) F) C) =C4) =O) C=C3) NN=C2) =CN=C1
Molecular Formula
C25H22ClF3N6O3
Molecular Weight
546.93
Storage Conditions
-20°C
Notes
For research use only.

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