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Dactinomycin

CAT: 0013-GTR19254582-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19254582-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Dactinomycin D (Actinomycin IV) is an antibiotic and autophagy activator produced by Streptomyces bacteria fermentation, which inhibits transcription and replication by inserting into the DNA double helix, and can also promote p53 phosphorylation and accumulation through MDM2 overexpression, serving as a chemotherapy drug for cancer treatment.
CAS Number
50-76-0
Product Name Alternative
Actinomycin IV, Dactinomycin D
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.33% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (2.63 mM) ; DMSO:80 mg/mL (63.72 mM)
Smiles
C (N[C@@H]1C (=O) N[C@H] (C (C) C) C (=O) N2[C@@] (CCC2) (C (=O) N (C) CC (=O) N (C) [C@@H] ([C@@H] (C) C) C (=O) O[C@@H]1C) [H]) (=O) C=3C=4C (OC=5C (N4) =C (C (N[C@@H]6C (=O) N[C@H] (C (C) C) C (=O) N7[C@@] (CCC7) (C (=O) N (C) CC (=O) N (C) [C@@H] ([C@H] (C) C) C (=O) O[C@@H]6C) [H]) =O) C=CC5C) =C (C) C (=O) C3N
Molecular Formula
C62H86N12O16
Molecular Weight
1255.42
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Notes
For research use only.

Alternative Products

CatalogName
AR-A05573-01Dactinomycin
A0850-01Actinomycin D (Dactinomycin)
MBS651300-01Actinomycin D (Streptomyces antibioticus, Dactinomycin, Actinomycin IV, Actinomycin C1)

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