Cloperastine (hydrochloride) (Standard)

• UNSPSC Description:

  Cloperastine (hydrochloride) (Standard) is the analytical standard of Cloperastine (hydrochloride). This product is intended for research and analytical applications. Cloperastine hydrochloride inhibits the hERG K+ currents in a concentration-dependent manner with an IC50 value of 27 nM[1].

• Target Antigen:

  Potassium Channel

• Type:

  Reference Standards

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/cloperastine-hydrochloride-standard.html

• Smiles:

  ClC1=CC=C(C(C2=CC=CC=C2)OCCN3CCCCC3)C=C1.[H]Cl

• Molecular Weight:

  366.32

• References & Citations:

  [1]Takahara A, et al. Effects of the antitussive drug cloperastine on ventricular repolarization in halothane-anesthetized guinea pigs. J Pharmacol Sci. 2012;120(3):165-75.|[2]Catania MA, et al. Pharmacological and clinical overview of cloperastine in treatment of cough. Ther Clin Risk Manag. 2011;7:83-92.

• Shipping Conditions:

  Room temperature

• CAS Number:

  14984-68-0