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AMG PERK 44

CAT: 0013-GTR19244403-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19244403-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AMG PERK 44 is an orally active and highly selective PERK inhibitor with an IC50 of 6 nM. AMG PERK 44 has 1000-fold and 160-fold selectivity over GCN2 (IC50=7300 nM) and B-Raf (IC50 >1000 nM), respectively. AMG PERK 44 induces autophagy.
CAS Number
1883548-84-2
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 25 mg/mL (44.56 mM; Ultrasonic)
Smiles
Cl.Cc1ccc2cc (ccc2n1) -c1c (C) ccc (C (=O) c2c (-c3ccccc3) n (C) n (-c3ccccc3) c2=O) c1N
Molecular Formula
C34H29ClN4O2
Molecular Weight
561.07
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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