Products for Research Use Only
RegisterLogin

(Rac) -MEM 1003

CAT: 0804-HY-121604-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-121604-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
(Rac) -MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca2+ channel antagonist and has the potential for Alzheimer’s disease research[1].
CAS Number
165187-25-7
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rac-mem-1003.html
Purity
99.64
Solubility
DMSO : 125 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(OCCOC)C1=C(NC(C)=C(C1C2=CC=CC(C#N)=C2Cl)C(OC(C)C)=O)C
Molecular Formula
C22H25ClN2O5
Molecular Weight
432.90
References & Citations
[1]Gregory M Rose, et al. Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28 (5) :766-73.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
L-type calcium channel

Chemical Information

(Rac)-MEM 1003
CAS Number165187-25-7
PubChem CID9802887
IUPAC Name3-O-(2-methoxyethyl) 5-O-propan-2-yl 4-(2-chloro-3-cyanophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
Molecular FormulaC22H25ClN2O5
Molecular Weight432.9
XLogP3.2
Topological Polar Surface Area97.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Heavy Atom Count30
Formal Charge0
Complexity780
SMILES
CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC(=C2Cl)C#N)C(=O)OCCOC
InChI
InChI=1S/C22H25ClN2O5/c1-12(2)30-22(27)18-14(4)25-13(3)17(21(26)29-10-9-28-5)19(18)16-8-6-7-15(11-24)20(16)23/h6-8,12,19,25H,9-10H2,1-5H3
InChIKey
GTIKSQYSAKETQA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (Rac)-MEM 1003
CAS: 165187-25-7
CID: 9802887
Formula: C22H25ClN2O5
MW: 432.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight432.9
XLogP33.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count9
Exact Mass432.1451996
Monoisotopic Mass432.1451996
Topological Polar Surface Area97.7 Ų
Heavy Atom Count30
Formal Charge0
Complexity780
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-160550DPM-1003
HY-149028Mem-C1C18
HY-W328402-01(Rac) -LB-100
HY-145817-01(Rac) -lunresertib
HY-135653A-01(Rac) -EC5026
HY-103519-01Rac-BHFF
HY-116463D-01(Rac) -E1R
HY-141495-01(Rac) -Razpipadon
HY-116830A(Rac) -BRD0705
HY-160187A-01(Rac) -AAA

Alternative Products

CatalogName
T28013-01(Rac) -MEM 1003
MBS5777712(Rac)-MEM 1003
B4904-100ACTB-1003
T204522-01DPM-1003
MBS3603199MDVN-1003
WQB91242-01TC-G 1003
323688Met (Ab-1003)
A53177-100ULMET (Ab-1003) Antibody
A14431-25EOC317 (ACTB-1003) 25mg
A14431-1EOC317 (ACTB-1003) 1mg

Popular Products