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LDN-193189 2HCl

CAT: 0013-GTR19244110-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0013-GTR19244110-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LDN-193189 (dihydrochloride) is a potent selective BMP type I receptor (BMP I) inhibitor. LDN-193189 efficiently inhibits transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 values of 5 nM and 30 nM, respectively. LDN-193189 can be used for the research of bone morphogenetic protein signalling, such as fibrodysplasia ossificans progressiva.
CAS Number
1435934-00-1
Purity
>98% (HPLC)
Solubility
In Vitro: H2O : 11.11 mg/mL (23.17 mM; Ultrasonic) DMSO : 10 mg/mL (20.86 mM; Ultrasonic (<60°C)
Smiles
C1 (C2=C3N=CC (C4=CC=C (N5CCNCC5) C=C4) =CN3N=C2) =C6C=CC=CC6=NC=C1.Cl.Cl
Molecular Formula
C25H24Cl2N6
Molecular Weight
479.4
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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