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PA-8

CAT: 0013-GTR19243989-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19243989-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PA-8 is a potent, selective and orally active PACAP type I (PAC1) receptor antagonist. PA-8 inhibits the phosphorylation of CREB induced by PACAP in PAC1-, but not VPAC1- or VPAC2-receptor. PA-8 also inhibits PACAP-induced cAMP elevation with an IC50 of 2 nM.
CAS Number
878437-15-1
Purity
>98% (HPLC)
Solubility
In Vitro: DMSO : 25 mg/mL (73.02 mM; Ultrasonic (<60°C)
Smiles
COc1cc (ccc1OCC=C) C1CC (=O) Nc2nc (N) [nH]c (=O) c12
Molecular Formula
C17H18N4O4
Molecular Weight
342.35
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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