Products for Research Use Only

2-O-Methyl-5-iodouridine

CAT: 0013-GTR19243386-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19243386-01Size:50 mg
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Description
2’-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
CAS Number
34218-84-3
Purity
>98% (HPLC)
Smiles
O (C) [C@H]1[C@@H] (O[C@H] (CO) [C@H]1O) N2C (=O) NC (=O) C (I) =C2
Molecular Formula
C10H13IN2O6
Molecular Weight
384.12
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

Chemical Information

5-Iodo-2'-O-methyluridine
CAS Number34218-84-3
PubChem CID10317833
IUPAC Name1-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-5-iodopyrimidine-2,4-dione
Molecular FormulaC10H13IN2O6
Molecular Weight384.12
XLogP-1.4
Topological Polar Surface Area108
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count19
Formal Charge0
Complexity428
SMILES
CO[C@@H]1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)I)CO)O
InChI
InChI=1S/C10H13IN2O6/c1-18-7-6(15)5(3-14)19-9(7)13-2-4(11)8(16)12-10(13)17/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6-,7-,9-/m1/s1
InChIKey
PLVDDNNLEWFJNQ-JXOAFFINSA-N
Chemical Structure
2D Structure
2D structure of 5-Iodo-2'-O-methyluridine
CAS: 34218-84-3
CID: 10317833
Formula: C10H13IN2O6
MW: 384.12
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight384.12
XLogP3-1.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass383.98183
Monoisotopic Mass383.98183
Topological Polar Surface Area108 Ų
Heavy Atom Count19
Formal Charge0
Complexity428
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes