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MRK-016

CAT: 0013-GTR19243330-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19243330-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MRK-016 is a potent, brain-penetrant, and orally bioavailable inverse agonist of the GABAA α5 receptor (IC50=3 nM) . It enhances hippocampal LTP in vitro and demonstrates potential for cognitive enhancement, antidepressant-like effects, and analgesia in preclinical models.
CAS Number
342652-67-9
Product Name Alternative
MRK 016, MRK016, MRK-016
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.76% (May vary between batches)
Solubility
DMSO:40 mg/mL (108.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.43 mM)
Smiles
N=1N=C (C2=NOC (=C2) C) N3N=C (OCC4=NC=NN4C) C (=C3C1) C (C) (C) C
Molecular Formula
C17H20N8O2
Molecular Weight
368.39
Storage Conditions
-20°C
Notes
For research use only.

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