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12 (S) -HHT

CAT: 0013-GTR19243181-01Size: 25 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19243181-01Size:25 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
12 (S) -HHT is an endogenous cyclooxygenase-derived metabolite of arachidonic acid and a BLT2 receptor agonist. It supports epithelial homeostasis and modulates inflammation, notably by upregulating MKP-1 to suppress the p38 MAPK/NF-κB pathway and IL-6 production, as demonstrated in UVB-irradiated HaCaT keratinocyte studies.
CAS Number
54397-84-1
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.45% (May vary between batches)
Smiles
[C@@H] (/C=C/C=C/C/C=C\CCCC (O) =O) (CCCCC) O
Molecular Formula
C17H28O3
Molecular Weight
280.4
Storage Conditions
-20°C
Notes
For research use only.

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A0855-91BActivin A Receptor, Type II-like 1 (Activin receptor-like kinase 1, ACVRL1, HHT, ALK1, HHT2, ORW2, SKR3, ALK-1, ACVRLK1, Activin A receptor, type II-like kinase 1) discontinued
A135997Dalantercept Biosimilar (, Fusion - [ACVRL1 (activin A receptor like type 1, activin receptor-like kinase 1, ACVRLK1, ALK1, ALK-1, serine/threonine-protein kinase receptor R3, SKR3, HHT, HHT2, ORW2) ]2 - IGHG1 Fc (Fragment constant) )
207469-HRPACVRL1 (Activin A Receptor Type II-like 1, TGF-B Superfamily Receptor Type I, Activin A Receptor, Type II-like Kinase 1, Serine/Threonine-Protein Kinase Receptor R3, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I) (HRP)

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