SK-124

CAT: 0013-GTR19242125-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19242125-01Size:25 mg

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Description

SK-124 is a potent and selective small molecule inhibitor of salt-inducible kinase (SIK) . It is a valuable research tool for investigating SIK signaling pathways in both cellular and animal models, particularly in studies of metabolism, inflammation, and bone biology.

CAS Number

2760404-50-8

Smiles

N=1N=C (OC1C=2C (OC) =CC (=CC2OC) C3=CN=C4C=C (C=CN43) C=5C=NN (C5) C) CC

Molecular Formula

C23H22N6O3

Molecular Weight

430.46

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

2-(2,6-Dimethoxy-4-(7-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)phenyl)-5-ethyl-1,3,4-oxadiazole

CAS Number	2760404-50-8
PubChem CID	164039567
IUPAC Name	2-[2,6-dimethoxy-4-[7-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl]phenyl]-5-ethyl-1,3,4-oxadiazole
Molecular Formula	C23H22N6O3
Molecular Weight	430.5
XLogP	3.6
Topological Polar Surface Area	92.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Heavy Atom Count	32
Formal Charge	0
Complexity	615

SMILES

CCC1=NN=C(O1)C2=C(C=C(C=C2OC)C3=CN=C4N3C=CC(=C4)C5=CN(N=C5)C)OC

InChI

InChI=1S/C23H22N6O3/c1-5-21-26-27-23(32-21)22-18(30-3)8-15(9-19(22)31-4)17-12-24-20-10-14(6-7-29(17)20)16-11-25-28(2)13-16/h6-13H,5H2,1-4H3

InChIKey

VOYZWDQJVPQGCO-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2760404-50-8

CID: 164039567

Formula: C23H22N6O3

MW: 430.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	430.5
XLogP3	3.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	430.17533859
Monoisotopic Mass	430.17533859
Topological Polar Surface Area	92.5 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	615
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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GTR19197531-01	HIE-124
GTR19238641-01	EGFR-IN-124
GTR19162264-01	CHIR-124
GTR19201299-01	EUK 124
GTR19242582-01	FPA-124
GTR19171929-01	CHIR-124

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T202425-01	SK-124
B7222-1	FPA 124
A8394-5.1	CHIR-124
HY-15369-01	FPA-124
HY-W008292-01	Carbostyril 124
HY-129451	HIE-124
T200720-01	EGFR-IN-124
T22773-01	EUK 124
9421-50	PTC-124
2174-5	EUK-124

SK-124

Chemical Information

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