Products for Research Use Only

LC-04-045

CAT: 0013-GTR19249489-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249489-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LC-04-045 is a potent and selective molecular glue degrader targeting NEK7, achieving 90% degradation at 7 nM in MOLT-4 cells via the UPS. It effectively inhibits IL-1β and IL-18 secretion, making it a valuable tool for studying NLRP3 inflammasome biology and inflammatory disease mechanisms.
Field of Research
Immunology & Inflammation, Signal Transduction
Molecular Formula
C32H28ClN5O3
Molecular Weight
566.05
Storage Conditions
-20°C
Notes
For research use only.