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GSK3β-IN-2

CAT: 0013-GTR19249316-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249316-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK3β-IN-2 (S01) is a potent GSK3β inhibitor (IC50 = 0.35 nM) that activates Wnt/β-catenin signaling to promote neurogenesis. It reduces Aβ-induced tau phosphorylation at Ser396, decreasing neurofibrillary tangles, and has been shown to ameliorate Alzheimer's-related phenotypes in a zebrafish model.
CAS Number
3068378-38-8
Field of Research
Signal Transduction, Stem Cell & Developmental Biology
Smiles
O=C (NC=1C=NC=CC1C=2C=CC=CC2) C3=CNC4=NC=C (C=C43) C=5C=CC=CC5
Molecular Formula
C25H18N4O
Molecular Weight
390.437
Storage Conditions
-20°C
Notes
For research use only.

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