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MORF-627

CAT: 0013-GTR19241248-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19241248-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MORF-627 is a potent and selective oral inhibitor of integrin αvβ6, blocking its ligand binding and TGF-β1 activation with low nanomolar IC50 values. It consequently inhibits downstream SMAD2/3 phosphorylation and has demonstrated efficacy in ameliorating pulmonary fibrosis in a murine bleomycin model, supporting its research use in fibrotic disease studies.
CAS Number
2412688-16-3
Field of Research
Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
[C@@H] (C (O) =O) (C1=C ([C@@H]2CCC3 (CC3) CO2) C=CC (F) =C1) N4C[C@H] (OCCCCC=5NC=6C (=CC5) CCCN6) CC4
Molecular Formula
C31H40FN3O4
Molecular Weight
537.67
Storage Conditions
-20°C
Notes
For research use only.

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