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EGFR-IN-134

CAT: 0013-GTR19240544-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19240544-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-134 is a potent triazoloquinoline-based EGFR inhibitor (IC50: 0.023 μM) that exhibits anticancer activity by inducing apoptosis, necrosis, and G2/M cell cycle arrest. It modulates key apoptotic proteins, including downregulating Bcl-2 and upregulating p53, Bax, and caspases. This compound is a valuable tool for in vitro cancer research, particularly in studying EGFR-driven proliferation and cell death mechanisms.
Field of Research
Cardiovascular Research, Cell Biology, Protein Biochemistry, Signal Transduction
Smiles
O=C (C1=NN (C2=CC=C ([N+] ([O-]) =O) C=C2) C3N1CCC4=C3C=C (OC) C (OC) =C4) /C=C/C5=CN (C6=CC=CC=C6) N=C5C7=CC=CC=C7
Molecular Formula
C36H30N6O5
Molecular Weight
626.66
Storage Conditions
-20°C
Notes
For research use only.

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