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TGase2-IN-1

CAT: 0013-GTR19240519-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19240519-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TGase2-IN-1 (Compound 22) is an orally bioavailable (74.6%) TGase2 inhibitor with an IC50 of 1.12 μM, demonstrating potent activity (IC50 0.07 μM) in human retinal endothelial cells. It effectively reduces retinal vascular leakage in a Streptozotocin-induced diabetic mouse model, supporting research in diabetic retinopathy and vascular biology.
CAS Number
2244702-64-3
Field of Research
Protein Biochemistry
Smiles
O=C1C=C (N) C (=O) C2=NC (=CC=C12) C=3C=CC (OC4CCN (CC4) C (C) C) =CC3
Molecular Formula
C23H25N3O3
Molecular Weight
391.46
Storage Conditions
-20°C
Notes
For research use only.

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