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SJ46421

CAT: 0013-GTR19239795-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239795-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SJ46421 is a potent PROTAC derived from (+) -JQ-1 that selectively recruits the E3 ligase KLHDC2 to degrade BRD2/3/4 BD2 domains. It demonstrates high ternary complex stability with an IC50 of 7.8 nM, making it a valuable chemical probe for BET protein function studies in cancer and epigenetic research, applicable in both cellular and biochemical assays.
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Molecular Formula
C42H41ClN8O5S2
Molecular Weight
837.41
Storage Conditions
-20°C
Notes
For research use only.

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