YD54

CAT: 0013-GTR19239546-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19239546-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

YD54 is a potent and selective SMARCA2-targeting PROTAC degrader with a DC50 of 3.5 nM. It is a valuable chemical probe for investigating BRM function in oncology and epigenetics research, supporting both in vitro and in vivo degradation studies.

CAS Number

2951015-30-6

Field of Research

Pharmacology & Drug Discovery

Smiles

O=C1C=2C=CC=C (OCCN3CCN (C4=CC=C (C=C4F) CN5CCN (C=6C=C (N=NC6N) C7=CC=CC=C7O) CC5) CC3) C2C (=O) N1C8C (=O) NC (=O) CC8

Molecular Formula

C40H42FN9O6

Molecular Weight

763.82

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

4-(2-(4-(4-((4-(3-Amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)methyl)-2-fluorophenyl)piperazin-1-yl)ethoxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

CAS Number	2951015-30-6
PubChem CID	168968806
IUPAC Name	4-[2-[4-[4-[[4-[3-amino-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]-2-fluorophenyl]piperazin-1-yl]ethoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
Molecular Formula	C40H42FN9O6
Molecular Weight	763.8
XLogP	2.1
Topological Polar Surface Area	178
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	10
Heavy Atom Count	56
Formal Charge	0
Complexity	1410

SMILES

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCN4CCN(CC4)C5=C(C=C(C=C5)CN6CCN(CC6)C7=CC(=NN=C7N)C8=CC=CC=C8O)F

InChI

InChI=1S/C40H42FN9O6/c41-28-22-25(24-47-14-18-49(19-15-47)32-23-29(44-45-37(32)42)26-4-1-2-6-33(26)51)8-9-30(28)48-16-12-46(13-17-48)20-21-56-34-7-3-5-27-36(34)40(55)50(39(27)54)31-10-11-35(52)43-38(31)53/h1-9,22-23,31,51H,10-21,24H2,(H2,42,45)(H,43,52,53)

InChIKey

WBWCGTJXNCHFJI-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2951015-30-6

CID: 168968806

Formula: C40H42FN9O6

MW: 763.8

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	763.8
XLogP3	2.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	14
Rotatable Bond Count	10
Exact Mass	763.32420826
Monoisotopic Mass	763.32420826
Topological Polar Surface Area	178 Å²
Heavy Atom Count	56
Formal Charge	0
Complexity	1410
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
E8293	YD54

YD54

Chemical Information

Alternative Products

Popular Products