Products for Research Use Only

HPG1860

CAT: 0013-GTR19239541-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239541-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPG1860 is a potent FXR agonist with an EC50 of 18 nM in cellular reporter assays. In a mouse NASH model, it significantly lowers serum ALT and cholesterol, while reducing hepatic steatosis, inflammation, and fibrosis, demonstrating therapeutic potential for metabolic liver disease research.
CAS Number
2226133-29-3
Field of Research
Metabolism Research
Smiles
C (C=1C (=NOC1C2CC2) C3=C (Cl) C=CC=C3Cl) N4C[C@@H] (C) N (CC4) C5=NC=6C (S5) =CC (C (O) =O) =CC6OC
Molecular Formula
C27H26Cl2N4O4S
Molecular Weight
573.49
Storage Conditions
-20°C
Notes
For research use only.

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