PQA-18

CAT: 0013-GTR19239533-03Size: 100 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19239533-03Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

PQA-18 is a potent and selective PAK2 inhibitor (IC50 = 10 nM) with demonstrated immunosuppressive activity. It suppresses IL-2 production in T-cells in vitro and shows efficacy in vivo by ameliorating atopic dermatitis in mice and improving graft survival in rat transplantation models.

CAS Number

1604678-82-1

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Smiles

O=C (OCC=C (C) C) C=1N=C2C (OCC=C (C) C) =CC=CC2=C (OCC=C (C) C) C1

Molecular Formula

C25H31NO4

Molecular Weight

409.52

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

3-Methylbut-2-enyl 4,8-bis(3-methylbut-2-enoxy)quinoline-2-carboxylate

CAS Number	1604678-82-1
PubChem CID	73602831
IUPAC Name	3-methylbut-2-enyl 4,8-bis(3-methylbut-2-enoxy)quinoline-2-carboxylate
Molecular Formula	C25H31NO4
Molecular Weight	409.5
XLogP	6.8
Topological Polar Surface Area	57.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Heavy Atom Count	30
Formal Charge	0
Complexity	640

SMILES

CC(=CCOC1=CC=CC2=C1N=C(C=C2OCC=C(C)C)C(=O)OCC=C(C)C)C

InChI

InChI=1S/C25H31NO4/c1-17(2)10-13-28-22-9-7-8-20-23(29-14-11-18(3)4)16-21(26-24(20)22)25(27)30-15-12-19(5)6/h7-12,16H,13-15H2,1-6H3

InChIKey

APPXFGJVXDYNBO-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1604678-82-1

CID: 73602831

Formula: C25H31NO4

MW: 409.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	409.5
XLogP3	6.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	10
Exact Mass	409.22530847
Monoisotopic Mass	409.22530847
Topological Polar Surface Area	57.7 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	640
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19194971	CP-18 F-18
GTR19231778	18:0-18:2 PE
GTR18985472	Interleukin-18 (IL-18) Antigen
GTR19248875-01	18:0-18:2 PE
GTR18574488	Recombinant Keratin 18 Antibody / Cytokeratin 18
GTR19220954-01	18:0, 18:1 PS sodium
GTR18574487	Recombinant Keratin 18 Antibody / Cytokeratin 18
GTR19249353-01	18:0-18:1 PA sodium
GTR18082533-01	Recombinant Keratin 18 Antibody / Cytokeratin 18
GTR19253107-01	18-CoA-18-oxo-dinor-LTB4

Alternative Products

Catalog	Name
T201360-01	PQA-18
TRC-S686499-5MG	Octadecanoic-18,18,18-d3 Acid
HY-W011222S1-01	1-Bromooctadecane-18,18,18-d3
sc-236934	Stearic acid-18,18,18-d3
T886456	Glyceryl Tri(octadecanoate-18,18,18-d3)
MBS343012-01	Cytokeratin-18 (CK-18)
MO-C40094A-01	Interleukin-18 (IL-18)
MM-1009-02	Cytokeratin 18 (CK 18)
MBS5780661	CP-18 F-18
228184	Cytokeratin 18 (Keratin 18)

PQA-18

Chemical Information

Related Products

Alternative Products

Popular Products