Products for Research Use Only

PQA-18

CAT: 0013-GTR19239533-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239533-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PQA-18 is a potent and selective PAK2 inhibitor (IC50 = 10 nM) with demonstrated immunosuppressive activity. It suppresses IL-2 production in T-cells in vitro and shows efficacy in vivo by ameliorating atopic dermatitis in mice and improving graft survival in rat transplantation models.
CAS Number
1604678-82-1
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Smiles
O=C (OCC=C (C) C) C=1N=C2C (OCC=C (C) C) =CC=CC2=C (OCC=C (C) C) C1
Molecular Formula
C25H31NO4
Molecular Weight
409.52
Storage Conditions
-20°C
Notes
For research use only.