NHTD

CAT: 0013-GTR19239269-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19239269-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

NHTD is a research compound that inhibits KRAS-PDEδ interaction by binding to the isoprenyl pocket of PDEδ, disrupting KRAS localization. This mechanism suppresses proliferation and promotes apoptosis in KRAS-mutant cells, making it a tool for studying KRAS-driven cancers like NSCLC in vitro and in vivo.

CAS Number

2540915-70-4

Field of Research

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Smiles

C (=N/NC (=O) C1=C (O) C=C (O) C=C1) \C2=C3C (OC4=C3CCCC4) =CC (C (C) (C) C) =C2O

Molecular Formula

C24H26N2O5

Molecular Weight

422.47

Storage Conditions

-20°C

Notes

For research use only.

Alternative Products

Catalog	Name
HY-164513	NHTD

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