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CIB-1476

CAT: 0013-GTR19239107-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239107-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CIB-1476 is a selective caspase-1 inhibitor that blocks NLRP3 inflammasome signaling, thereby suppressing IL-1β maturation, NF-κB activation, and GSDMD-driven pyroptosis. It demonstrates potent and durable anti-inflammatory effects, effectively reducing joint swelling in murine arthritis models, making it a valuable tool for studying inflammasome-related pathways in vivo and in vitro.
Field of Research
Cell Biology, Immunology & Inflammation, Protein Biochemistry, Signal Transduction
Molecular Formula
C28H28N2O6S
Molecular Weight
520.6
Storage Conditions
-20°C
Notes
For research use only.

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