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AP-6

CAT: 0013-GTR19239010-02Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239010-02Size:5 mg
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Description
AP-6 is a selective TMEM175 inhibitor that acutely enhances lysosomal catabolism and accelerates macrophage digestive activity. This compound is a valuable research tool for studying lysosomal function in Parkinson's disease models, with applications in both in vitro and in vivo experimental systems.
CAS Number
1369963-51-8
Field of Research
Pharmacology & Drug Discovery
Purity
99.44% (May vary between batches)
Smiles
N=1C=CC (N) =CC1C=2C=CC=C (C2) C=3N=CC=C (N) C3
Molecular Formula
C16H14N4
Molecular Weight
262.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

2,2'-(1,3-Phenylene)bis[4-pyridinamine]
CAS Number1369963-51-8
PubChem CID171905873
IUPAC Name2-[3-(4-amino-2-pyridinyl)phenyl]pyridin-4-amine
Molecular FormulaC16H14N4
Molecular Weight262.31
XLogP1.7
Topological Polar Surface Area77.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity281
SMILES
C1=CC(=CC(=C1)C2=NC=CC(=C2)N)C3=NC=CC(=C3)N
InChI
InChI=1S/C16H14N4/c17-13-4-6-19-15(9-13)11-2-1-3-12(8-11)16-10-14(18)5-7-20-16/h1-10H,(H2,17,19)(H2,18,20)
InChIKey
XLXGLQRJMSGVPH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2,2'-(1,3-Phenylene)bis[4-pyridinamine]
CAS: 1369963-51-8
CID: 171905873
Formula: C16H14N4
MW: 262.31
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight262.31
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass262.121846464
Monoisotopic Mass262.121846464
Topological Polar Surface Area77.8 Ų
Heavy Atom Count20
Formal Charge0
Complexity281
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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HY-161949-01AP-6
sc-136338AP-3σ (6)
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MBS6134055-01Syntaxin 6 (Syntaxin-6, STX6) (AP)
MBS6242017-01Interleukin-6 (IL-6, IL6) (AP)
MBS6260120-01Adenovirus, Type 6 (AP)
MBS6241547-01GRK 4-6 (AP)
sc-136338 HRPAP-3σ (6) HRP
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