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LCS-1

CAT: 0013-GTR19239501-03Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19239501-03Size:10 mg
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Description
LCS-1 is a pyridazinone-based, selective SOD1 inhibitor. It exhibits trypanocidal activity at high doses and induces ROS-dependent cell death in glioma models, leading to the degradation of PARP and BRCA1. This compound is a useful research tool for studying oxidative stress mechanisms in cancer and parasitic diseases.
CAS Number
41931-13-9
Product Name Alternative
LCS1
Field of Research
Cell Biology
Purity
99.28% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2 mg/mL (7.84 mM) ; DMSO:40 mg/mL (156.8 mM)
Smiles
O=C1C (Cl) =C (Cl) C=NN1C2=CC=CC (=C2) C
Molecular Formula
C11H8Cl2N2O
Molecular Weight
255.1
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4,5-Dichloro-2-(3-methylphenyl)pyridazin-3-one
CAS Number41931-13-9
PubChem CID779573
IUPAC Name4,5-dichloro-2-(3-methylphenyl)pyridazin-3-one
Molecular FormulaC11H8Cl2N2O
Molecular Weight255.10
XLogP2.4
Topological Polar Surface Area32.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Heavy Atom Count16
Formal Charge0
Complexity365
SMILES
CC1=CC(=CC=C1)N2C(=O)C(=C(C=N2)Cl)Cl
InChI
InChI=1S/C11H8Cl2N2O/c1-7-3-2-4-8(5-7)15-11(16)10(13)9(12)6-14-15/h2-6H,1H3
InChIKey
SYUPLLHVMCLXEM-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4,5-Dichloro-2-(3-methylphenyl)pyridazin-3-one
CAS: 41931-13-9
CID: 779573
Formula: C11H8Cl2N2O
MW: 255.10
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight255.10
XLogP32.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass254.0013683
Monoisotopic Mass254.0013683
Topological Polar Surface Area32.7 Ų
Heavy Atom Count16
Formal Charge0
Complexity365
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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