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AZ'3137

CAT: 0013-GTR19238107-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238107-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ'3137 (Compound 22) is a potent, orally bioavailable PROTAC that degrades the androgen receptor (AR) with a DC50 of 22 nM. It demonstrates anti-proliferative activity in LNCaP cells (GI50 74 nM) and has shown efficacy in suppressing AR signaling and tumor growth in prostate cancer mouse models, supporting its use in oncology research.
CAS Number
2960179-55-7
Smiles
N#CC1=CC=C (C (F) =C1C (F) (F) F) N2CCC (C3=CC=C (C=C3) N4CCC (CN5CCN (C6=CC (OC) =C7C (=O) N (CC7=C6) C8C (=O) NC (=O) CC8) CC5) CC4) CC2
Molecular Formula
C43H47F4N7O4
Molecular Weight
801.87
Storage Conditions
-20°C
Notes
For research use only.

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