Products for Research Use Only
RegisterLogin

GPR17 modulator-1

CAT: 0013-GTR19238040-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19238040-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
GPR17 Modulator-1 (Compound 2-046) is a potent, brain-penetrant small molecule antagonist of human GPR17 (IC50 < 10 nM) . Its moderate PK profile supports its use in both cellular assays and in vivo rodent models for researching neuroinflammatory and demyelinating diseases.
CAS Number
3039853-91-0
Field of Research
Signal Transduction
Smiles
O=S (=O) (NC1=CC (F) =C (N=C1OC) OCC (F) F) C=2C=NN3C=C (Cl) C=CC23
Molecular Formula
C15H12ClF3N4O4S
Molecular Weight
436.79
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

GPR17 modulator-1
CAS Number3039853-91-0
PubChem CID172419492
IUPAC Name6-chloro-N-[6-(2,2-difluoroethoxy)-5-fluoro-2-methoxy-3-pyridinyl]pyrazolo[1,5-a]pyridine-3-sulfonamide
Molecular FormulaC15H12ClF3N4O4S
Molecular Weight436.8
XLogP2.7
Topological Polar Surface Area103
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Heavy Atom Count28
Formal Charge0
Complexity629
SMILES
COC1=NC(=C(C=C1NS(=O)(=O)C2=C3C=CC(=CN3N=C2)Cl)F)OCC(F)F
InChI
InChI=1S/C15H12ClF3N4O4S/c1-26-15-10(4-9(17)14(21-15)27-7-13(18)19)22-28(24,25)12-5-20-23-6-8(16)2-3-11(12)23/h2-6,13,22H,7H2,1H3
InChIKey
LWKOMJFDEJJLET-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of GPR17 modulator-1
CAS: 3039853-91-0
CID: 172419492
Formula: C15H12ClF3N4O4S
MW: 436.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight436.8
XLogP32.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass436.0219882
Monoisotopic Mass436.0219882
Topological Polar Surface Area103 Ų
Heavy Atom Count28
Formal Charge0
Complexity629
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19249861-01GPR17 antagonist 1
GTR19186183-01P2Y2R/GPR17 antagonist 1
GTR17697974GPR17 Antibody
GTR18896614-01GPR17 peptide
GTR18136633GPR17 Antibody
GTR18223492GPR17 Antibody
GTR18157256GPR17 Antibody
GTR17936054GPR17 Antibody
GTR17931112-01GPR17 Antibody
GTR18235033-01GPR17 Antibody

Alternative Products

CatalogName
HY-164311GPR17 modulator-1
AR-G02745-01GPR17 Impurity 1
HY-170589-01GPR17 antagonist 1
T62420-01P2Y2R/GPR17 antagonist 1
K0889402GPR17 sgRNA CRISPR Lentivector (Human) (Target 1)
K4318402Gpr17 sgRNA CRISPR Lentivector (Mouse) (Target 1)
K6688102Gpr17 sgRNA CRISPR Lentivector (Rat) (Target 1)
K0889406GPR17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)
K6688106Gpr17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
K4318406Gpr17 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

Popular Products