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D3S-001

CAT: 0013-GTR19237720-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237720-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D3S-001 is a potent and orally bioavailable KRASG12C inhibitor, demonstrating sub-nanomolar IC50 values in cellular assays and favorable metabolic stability. It shows promising pharmacokinetics and robust in vivo antitumor efficacy in mouse models, supporting its use in oncology research targeting RAS-driven cancers.
CAS Number
2914919-85-8
Field of Research
Signal Transduction
Smiles
C (OC1=NC (=C2C (=N1) C[C@H] (OC2) C3=C (C (F) (F) F) C (C) =CC (N) =C3F) N4C[C@H] (CC#N) N (C (C (=C) F) =O) CC4) [C@@]56N (C[C@H] (F) C5) CCC6
Molecular Formula
C32H35F6N7O3
Molecular Weight
679.66
Storage Conditions
-20°C
Notes
For research use only.

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