Products for Research Use Only

O-GlcNAcase-IN-2

CAT: 0013-GTR19238201-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238201-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
O-GlcNAcase-IN-2 is a potent, orally bioavailable, and brain-penetrant O-GlcNAcase inhibitor (IC50 = 4.93 nM) . It increases protein O-GlcNAcylation and modulates tau phosphorylation in cellular models, and has demonstrated efficacy in improving cognitive function in APP/PS1 transgenic mice, supporting its research application in Alzheimer's disease pathology.
Molecular Formula
C22H26N4OS
Molecular Weight
394.53
Storage Conditions
-20°C
Notes
For research use only.