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SMART1

CAT: 0013-GTR19237835-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237835-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SMART1 is a CRBN-dependent PROTAC that selectively degrades Smurf1. It demonstrates anti-tumor activity in KRAS-mutant colorectal cancer xenograft models by disrupting the PDK1-Akt signaling axis, making it a valuable tool for studying targeted protein degradation and oncogenic signaling in vitro and in vivo.
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C40H35N9O7
Molecular Weight
753.76
Storage Conditions
-20°C
Notes
For research use only.

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