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T638

CAT: 0013-GTR19236935-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236935-02Size:50 mg
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Description
T638 is a potent and selective topoisomerase II alpha (TOP2A) inhibitor with an IC50 of 0.7 μM. It effectively suppresses cancer cell proliferation in vitro and has demonstrated antitumor efficacy in preclinical in vivo models, making it a valuable chemical probe for oncology research.
CAS Number
2770585-67-4
Field of Research
Molecular Biology
Smiles
O=C (NC1=CC=C (C=C1N) NC=2C=CC=CC2) C3=CC=CNC3=S
Molecular Formula
C18H16N4OS
Molecular Weight
336.41
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(2-amino-4-anilinophenyl)-2-sulfanylidene-1H-pyridine-3-carboxamide
CAS Number2770585-67-4
PubChem CID163356001
IUPAC NameN-(2-amino-4-anilinophenyl)-2-sulfanylidene-1H-pyridine-3-carboxamide
Molecular FormulaC18H16N4OS
Molecular Weight336.4
XLogP2.7
Topological Polar Surface Area111
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Heavy Atom Count24
Formal Charge0
Complexity539
SMILES
C1=CC=C(C=C1)NC2=CC(=C(C=C2)NC(=O)C3=CC=CNC3=S)N
InChI
InChI=1S/C18H16N4OS/c19-15-11-13(21-12-5-2-1-3-6-12)8-9-16(15)22-17(23)14-7-4-10-20-18(14)24/h1-11,21H,19H2,(H,20,24)(H,22,23)
InChIKey
IIUONQJTTGSQCA-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(2-amino-4-anilinophenyl)-2-sulfanylidene-1H-pyridine-3-carboxamide
CAS: 2770585-67-4
CID: 163356001
Formula: C18H16N4OS
MW: 336.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight336.4
XLogP32.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass336.10448232
Monoisotopic Mass336.10448232
Topological Polar Surface Area111 Ų
Heavy Atom Count24
Formal Charge0
Complexity539
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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