T638

CAT: 0804-HY-164143-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-164143-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

T638 is a topoisomerase II (TOP2) inhibitor. T638 inhibits TOP2A activity with a IC50 of 0.7 uM. T638 strongly inhibits cancer cell growth[1].

CAS Number

2770585-67-4

UNSPSC

12352005

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/t638.html

Purity

98.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=CNC1=S)NC2=CC=C(NC3=CC=CC=C3)C=C2N

Molecular Formula

C18H16N4OS

Molecular Weight

336.41

References & Citations

[1]Matias-Barrios VM, et al. Optimization of New Catalytic Topoisomerase II Inhibitors as an Anti-Cancer Therapy. Cancers (Basel) . 2021 Jul 22;13 (15) :3675.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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