T638

• UNSPSC Description:

  T638 is a topoisomerase II (TOP2) inhibitor. T638 inhibits TOP2A activity with a IC50 of 0.7 uM. T638 strongly inhibits cancer cell growth[1].

• Target Antigen:

  Topoisomerase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/t638.html

• Smiles:

  O=C(C1=CC=CNC1=S)NC2=CC=C(NC3=CC=CC=C3)C=C2N

• Molecular Weight:

  336.41

• References & Citations:

  [1]Matias-Barrios VM, et al. Optimization of New Catalytic Topoisomerase II Inhibitors as an Anti-Cancer Therapy. Cancers (Basel). 2021 Jul 22;13(15):3675.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2770585-67-4