Products for Research Use Only

SIC-19

CAT: 0013-GTR19236558-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19236558-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SIC-19 is a small molecule SIK2 inhibitor that induces SIK2 protein degradation via the ubiquitin-proteasome pathway. It demonstrates anti-proliferative activity in cancer cells and enhances sensitivity to PARP inhibitors like Olaparib in both in vitro models and in vivo ovarian cancer xenografts.
CAS Number
713112-69-7
Field of Research
Signal Transduction
Smiles
O=C (NC (=S) NNC (=O) C1=C (SC (=C1C2=CC=C (OC) C (OC) =C2) C) NC (=O) C=3C=CC=CC3) C=4C=CC=CC4
Molecular Formula
C29H26N4O5S2
Molecular Weight
574.67
Storage Conditions
-20°C
Notes
For research use only.