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IRAK4-IN-19

CAT: 0013-GTR19185347-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185347-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IRAK4-IN-19 is a potent and selective IRAK4 inhibitor (IC50 = 4.3 nM) that suppresses LPS-induced IL-23 production in immune cells like THP-1 cells. It has demonstrated efficacy in reducing arthritis severity in preclinical rodent models, making it a valuable chemical probe for researching autoimmune and inflammatory diseases.
Field of Research
Immunology & Inflammation, Signal Transduction
Molecular Formula
C25H26F2N8O
Molecular Weight
492.52
Storage Conditions
-20°C
Notes
For research use only.

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